Gamma-glutamyltransferase as a cardiovascular risk factor

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Gamma-glutamyltransferase as a cardiovascular risk factor.

The association of a novel factor with clinical vascular disease must meet the same high standard met by ‘traditional’ risk factors. Serum gamma-glutamyltransferase (GGT) activity is a low-cost, highly sensitive laboratory test: though it is currently considered as an index of hepatobiliary dysfunction and alcohol abuse, pathology studies from our group since 1998 have indicated its possible ro...

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Gamma-glutamyltransferase to determine cardiovascular risk: shifting the paradigm forward.

Gamma-glutamyltransferase (GGT), regarded as a marker of excessive alcohol consumption or liver disturbances, is an enzyme catalyzing the first step in the extracellular degradation of the antioxidant glutathione (GSH) and may take part in atherogenesis. The marked relationship between GGT and the atherosclerotic process has shifted attention to the issue of whether its serum levels can aid in ...

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Serum Gamma-Glutamyltransferase as a Risk Factor of Ischemic Stroke Might Be Independent of Alcohol Consumption

Response We are not surprised by the very sensible question from Achard et al as to why selective AT1 receptor antagonists were not used in our experiments reported in Stroke.1 The reason for this decision is academically somewhat disappointing while unfortunately very relevant in the current era, with an increased awareness of the real value of intellectual property. Our request for losartan t...

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Serum gamma-glutamyltransferase as a risk factor of ischemic stroke might be independent of alcohol consumption.

Response We are not surprised by the very sensible question from Achard et al as to why selective AT1 receptor antagonists were not used in our experiments reported in Stroke.1 The reason for this decision is academically somewhat disappointing while unfortunately very relevant in the current era, with an increased awareness of the real value of intellectual property. Our request for losartan t...

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Serum Gamma-Glutamyltransferase as a Risk Factor of Ischemic Stroke Might

Response We are not surprised by the very sensible question from Achard et al as to why selective AT1 receptor antagonists were not used in our experiments reported in Stroke.1 The reason for this decision is academically somewhat disappointing while unfortunately very relevant in the current era, with an increased awareness of the real value of intellectual property. Our request for losartan t...

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ژورنال

عنوان ژورنال: European Heart Journal

سال: 2006

ISSN: 0195-668X,1522-9645

DOI: 10.1093/eurheartj/ehl151